Wyoming pneumonic plague 2021: Extra info

NewsDesk @bactiman63

In a follow-up on a pneumonic plague case reported in Wyoming final September 2021, the Centers for Disease Control and Prevention (CDC) printed a Notes from the sector in Friday’s Morbidity and Mortality Weekly Report (MMWR) that particulars the investigation.

The particular person was admitted to a Wyoming hospital following a 48-hour historical past of worsening cough, dyspnea, and acute onset of hemoptysis.


The affected person reported no current journey historical past or ailing contacts however famous interacting with two pet cats that have been ailing.

Health care suppliers initially suspected COVID-19 due to suitable signs, no historical past of COVID-19 vaccination, and elevated SARS-CoV-2 (the virus that causes COVID-19) neighborhood transmission in Wyoming throughout this era.

The authors write: Approximately 48 hours after symptom onset, the affected person acquired a destructive SARS-CoV-2 antigen check outcome at a supplier’s workplace. The affected person was hospitalized later that day for worsening signs and acquired two destructive SARS-CoV-2 laboratory-based nucleic acid amplification check outcomes. Lung imaging was in step with community-acquired pneumonia. Respiratory specimens examined destructive for frequent viral pathogens on a respiratory panel. Within 48 hours of admission, the affected person required mechanical air flow and developed sepsis. The affected person was handled for pneumonia and sepsis with azithromycin, piperacillin-tazobactam, and vancomycin. Seventy-two hours after the affected person was admitted to the hospital, blood and sputum cultures didn’t point out a causative pathogen. Because of the affected person’s historical past of publicity to cats that have been ailing, an infectious ailments specialist beneficial repeating a sputum tradition with Gram stain and empiric therapy with ciprofloxacin. Gram-negative bacilli have been detected, and the Wyoming Public Health Laboratory subsequently confirmed Yersinia pestis because the pathogen.

The Wyoming Department of Health  instantly performed interviews to find out publicity supply, establish shut contacts requiring postexposure prophylaxis (PEP), and information public well being prevention measures. Interviews with veterinary clinic employees members and assessment of information revealed that one cat had died from an undiagnosed extreme sickness after onset of respiratory signs; serologic testing of specimens from the surviving cat for Y. pestis by CDC was destructive. WDH interviews with native animal management and state wildlife officers revealed no identified epizootic close to the affected person’s residence, which was in a rural space of Wyoming; nonetheless, each pet cats have been identified to spend time indoors and outdoor and weren’t handled with flea management merchandise.

This is the second case of main pneumonic plague and the seventh of any type of plague in Wyoming’s documented historical past. Nationwide, 18 instances of pneumonic plague have been reported throughout 1942–2018.

Read extra at MMWR


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